The studies on the fluid environment of ascaris: influence of pH and effect of antibiotics and antimycotics (dehydroacetic acid) in fluid media upon the survival length and the duration of normal locomotion.

The typical locomotion of ascaris was found and studied by Kobayashi and Bando (1950) in a glass-tube of the appropriate diameter filled with Ringer or Bunge's solution. They also observed that santonin in vitro did not influence on survival-length of ascaris, but induced a spasmodic curling around the body of ascaris which seemed to be a kind of convulsion caused by the drug. It was supposed that the ascaris being convulsed by drug in vitro would be expelled out of the colon by the peristaltic movements of the small intestine ultimately (Kobayashi and Bando, 1950; Kobayashi et al., 1952). Thereafter the more details of ascaris's life under many different environments have been studied by us. The present report includes the studies on influence of pH of fluid, addition of antibiotics and antimycotics upon ascaris in vitro. This may be basic problems to be solved for the research works of ascaris in the human bowel.